New Yellow Fever Entry Requirements
Paraguay’s Ministry of Health has revised its yellow fever vaccination entry requirements, now requiring proof of vaccination from travelers coming from specific risk zones in just 5 countries: Bolivia, Brazil, Colombia, Guyana, and Peru. This is stricter than WHO’s standard recommendations and applies even to airport transit stops longer than 24 hours.
Who This Affects and What You Need
The new requirement targets travelers aged 1-59 years arriving from designated high-risk areas, including Santa Cruz Department in Bolivia, five specific states in Brazil (Amazonas, Minas Gerais, São Paulo, Rio Grande do Sul, and Roraima), six departments in Colombia, all of Guyana, and five regions in Peru. Notably, this also applies to Paraguayan citizens and residents traveling TO these risk zones.
Understanding Yellow Fever
Yellow fever is a serious mosquito-borne viral disease that can cause severe illness and death. While Paraguay has remained yellow fever-free since 2008, neighboring countries continue to report outbreaks. The vaccine is highly effective and provides lifelong protection with a single dose—but it must be given at least 10 days before travel to be valid for entry.
What Travelers Should Do
To ensure smooth entry into Paraguay and protect yourself against yellow fever, verify whether your departure location is in a designated risk zone. If so, get vaccinated at least 10 days before your trip and keep your International Certificate of Vaccination (yellow card) with your passport. No certificate means you may be denied entry or face mandatory health monitoring for up to 10 days.
TravelBug Health offers yellow fever vaccination along with expert travel health guidance to keep you safe on your journey. Contact us to ensure you have all the vaccines and documentation you need before you travel.
Related Travel Health Resources
Learn more about the Yellow Fever vaccination on our website or book an appointment here.
References:
The Rio Times. Paraguay’s New Health Entry Requirements: What You Need to Know. July 8, 2025.
U.S. CDC Yellow Book 2026. Paraguay Yellow Fever Information.

